There are simply too many inconsistencies with the hypothesis that most cancers arise specifically from gene or chromosomal defects. The most damming evidence against the gene theory comes from the nucleus/cytoplasmic transfer experiments. ... Just because the majority of cancer researchers do not question the theory that guides their work does not mean that the theory is correct. Indeed, it appears that the average cancer researcher is not guided by any grand theory, rather they formulate restricted hypotheses for the next few experiments and tend to go on collecting data without reference to the problem of carcinogenesis.